voomasinhVoom.RdComputes the observation level weight based on the mean-variance relationship.
asinhVoom(counts, design = NULL, sj, span = 0.5, plot = FALSE)
| counts | A numeric matrix of otu_table. |
|---|---|
| design | A design matrix with rows corresponding to samples and columns to coefficients to be estimated. Defaults to the unit vector meaning that samples are treated as replicates. |
| sj | A numeric vector containing library size normalization factor based on the median-ratio method. |
| span | A numeric. Width of the lowess smoothing window as a proportion. |
| plot | A logical, should a plot of the mean-variance trend be displayed? |
A matrix of variance stablized counts.